Ocular motor abnormalities in Huntington's disease

Ocular motor abnormalities in Huntington's disease

We review here the eye movements in patients with Huntington's disease (HD), concentrating upon saccades as they show the most prominent abnormalities. Inability to suppress reflexive glances to suddenly appearing novel visual stimuli and delayed initiation of voluntary saccades, including predictive saccades, are early and consistent findings. These two abnormalities can be interpreted in the ...

Ocular abnormalities in thin basement membrane disease.

AIM/BACKGROUND Alport syndrome is an X linked disease that results in renal failure, deafness, and ocular abnormalities including a dot and fleck retinopathy and anterior lenticonus. The ultrastructural appearance of the glomerular basement membrane in thin basement membrane disease (TBMD) resembles that seen in some patients with Alport syndrome, and in some cases this disease is inherited too...

Applying Bioinfomatics Strategies in Huntingtons Disease Research

Brain injury and ocular motor abnormalities in surviving preterm infants.

Editorials Brain injury and ocular motor abnormalities in surviving preterm infants Advances in neonatal care over the past 10 years have resulted in increased survival of very immature preterm infants but there has not been a corresponding improvement in neurodevelopmental outcome. 1 Serious neonatal morbidity is associated with decreasing gestational age. The survival of infants of extremely ...

Motor control abnormalities in Parkinson's disease.

The primary manifestations of Parkinson's disease are abnormalities of movement, including movement slowness, difficulties with gait and balance, and tremor. We know a considerable amount about the abnormalities of neuronal and muscle activity that correlate with these symptoms. Motor symptoms can also be described in terms of motor control, a level of description that explains how movement var...